This case study introduces you to Dr. E.L. Trudeau, who performed a seminal early experiment validating the germ theory of infection. Part I introduces Trudeau’s Rabbit Island experiment. Its results provided rational bases for the tuberculosis sanatorium movement of the late 19th and early 20th century. In Part I, you will learn about tuberculosis and some of the rudiments of experimental design and graphic analysis. Part II focuses on tuberculosis in its social context.